abstract：:Sarcoidosis is a granulomatous disease with an increased accumulation of T cells in lungs as a result of on-site proliferation and chemotaxis induced by chemokines. It has already been demonstrated that CCL3-5 levels were increased in BAL fluid of sarcoidosis patients. To analyze the expression of CCL3-5 chemokines by...

journal_title：International journal of immunopathology and pharmacology

authors： Barczyk A,Pierzchała E,Caramori G,Sozańska E

更新日期：2014-04-01 00:00:00

abstract：:To assess the rate of sexual distress, sexual dysfunction and relationship quality and their association with clinical variables in women with systemic sclerosis (SSc), 102 sexually active women with SSc were recruited. Sexual distress, sexual dysfunction and dissatisfaction with relationship quality were investigated...

journal_title：International journal of immunopathology and pharmacology

authors： Rosato E,Rossi C,Molinaro I,Di Giulio MA,Trombetta AC,Marra AM,Gigante A,Barbano B,Quarta S,Pisarri S,Afeltra A,Salsano F

更新日期：2014-04-01 00:00:00

abstract：:Involvement of imbalance between pro- and anti-inflammatory events has been reported in the developed pathogenesis after scorpion envenomation. The immunosuppressive and anti-inflammatory properties of tacrolimus (FK-506) have been investigated: i) to better understand evolution of signaling pathways which are involve...

journal_title：International journal of immunopathology and pharmacology

authors： Kabrine M,Laraba-Djebari F

更新日期：2014-01-01 00:00:00

abstract：:After birth various bacterial species, mainly streptococci, colonize the oral cavity and are frequently isolated from carious lesions in children. Previous studies suggest that an earlier colonization of a child's mouth by cariogenic organisms might be related to a higher risk of caries. The aim of this study is to as...

journal_title：International journal of immunopathology and pharmacology

authors： Duse M,Zicari AM,Berlutti F,Ernesti I,Occasi F,Leonardi L,Polimeni A

更新日期：2014-01-01 00:00:00

abstract：:When through the skin a foreign antigen enters it provokes an immune response and inflammatory reaction. Mast cells are located around small vessels that are involved in vasaldilation. They mature under the influence of local tissue to various cytokines. Human skin mast cells play an essential role in diverse physiolo...

journal_title：International journal of immunopathology and pharmacology

authors： Kritas SK,Saggini A,Varvara G,Murmura G,Caraffa A,Antinolfi P,Toniato E,Pantalone A,Neri G,Frydas S,Rosati M,Tei M,Speziali A,Saggini R,Pandolfi F,Cerulli G,Theoharides TC,Conti P

更新日期：2013-10-01 00:00:00

abstract：:Ink spot lentigo, also known as reticulated black solar lentigo, is a melanotic macula commonly described in fair-skinned individuals on sun-exposed areas of the body. Clinically it is a darkly pigmented type of solar lentigo; herein the term ink spot lentigo. In contrast to common solar lentigines, ink spot lentigo i...

journal_title：International journal of immunopathology and pharmacology

authors： Bottoni U,Nisticò S,Amoruso GF,Schipani G,Arcidiacono V,Scali E,Tassone P,Greco M,Amorosi A

更新日期：2013-10-01 00:00:00

abstract：:Pseudoxanthoma Elasticum-like Papillary Dermal Elastolysis (PXE-PDE) is a peculiar idiopathic elastolytic disorder that clinically resembles Psudoxanthoma elasticum(PXE). It is histologically characterized by a total or partial loss of elastic fibers in the papillary dermis. It more often affects elderly women and is ...

journal_title：International journal of immunopathology and pharmacology

authors： Pranteda G,Muscianese M,Marmo G,Fidanza L,Pranteda G,Tamburi F,Bottoni U,Nisticò S

更新日期：2013-10-01 00:00:00

abstract：:The beneficial effects of hot springs have been known for centuries and treatments with sulphurous thermal waters are recommended in a number of chronic pathologies as well as acute recurrent infections. However, the positive effects of the therapy are often evaluated in terms of subjective sense of wellbeing and symp...

journal_title：International journal of immunopathology and pharmacology

authors： Prandelli C,Parola C,Buizza L,Delbarba A,Marziano M,Salvi V,Zacchi V,Memo M,Sozzani S,Calza S,Uberti D,Bosisio D

更新日期：2013-07-01 00:00:00

abstract：:The aim of this experimental study was to evaluate the effects of nicotine on sperm motility and on non-conventional sperm parameters in vitro. Capacitated spermatozoa isolated from 10 normozoospermic, healthy, non-smoker men were evaluated. Spermatozoa were exposed to increasing concentrations of nicotine (0, 1, 10, ...

journal_title：International journal of immunopathology and pharmacology

authors： Condorelli RA,La Vignera S,Giacone F,Iacoviello L,Vicari E,Mongioi' L,Calogero AE

更新日期：2013-07-01 00:00:00

abstract：:We describe the case of a child affected by milk-protein induced enterocolitis, in which oral challenge with corn was performed without symptoms after a negative specific Atopy Patch Test. Food protein-induced enterocolitis syndrome (FPIES) is an uncommon nonIgE-mediated gastrointestinal food hypersensitivity of infan...

journal_title：International journal of immunopathology and pharmacology

authors： Scaparrotta A,Di Pillo S,Consilvio NP,Attanasi M,Cingolani A,Rapino D,Cerasa M,Pucci N,Di Gioacchino M,Chiarelli F

更新日期：2013-07-01 00:00:00

abstract：:More and more studies have demonstrated the anti-inflammatory effects of heparin. However, in the aspect of allergic airway inflammation, data about its daily use in animal model is scarce. To evaluate the efficacy of 22-day intranasal heparin administration in mite-induced airway allergic inflammation in BALB/c mice,...

journal_title：International journal of immunopathology and pharmacology

authors： Fu LS,Tsai JJ,Chen YJ,Lin HK,Tsai MC,Chang MD

更新日期：2013-04-01 00:00:00

abstract：:Although dental implants have undergone impressive evolution in recent years, periimplantitis still remains a relevant problem and information on the susceptibility of commercial implants to bacterial colonization is insufficient. This work evaluated the susceptibility of different commercial implants to bacterial col...

journal_title：International journal of immunopathology and pharmacology

authors： Passariello C,Pera F,Gigola P

更新日期：2013-04-01 00:00:00

abstract：:Non-cystic fibrosis bronchiectasis (nCFb) is an acquired condition of variable etiology. Medical treatment basically involves antibiotics and chest physiotherapy. An impaired mucociliary clearance seems to be one of the mechanisms behind nCFb, and inhaled therapy with mucoactive agents has frequently been used to try ...

journal_title：International journal of immunopathology and pharmacology

authors： Snijders D,Calgaro S,Bertozzi I,Quartesan S,Kozuh I,Lunardi F,Barbato A

更新日期：2013-04-01 00:00:00

abstract：:Asthma is a chronic airway inflammatory disease associated with airway hyperresponsiveness which affects subjects with genetic predisposition. An association has been reported between some polymorphisms in various cytokine genes and asthma. Most of them are single nucleotide polymorphisms (SNPs). These polymorphisms a...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardolo FL,Sorbello V,Silvestri M,Giacomelli M,Debenedetti VM,Malerba M,Ciprandi G,Rossi GA,Rossi A,Bontempelli M

更新日期：2013-01-01 00:00:00

abstract：:Dysregulation of the Axl receptor tyrosine kinase (RTK) has been implicated in the development and progression of a variety of malignancies. Axl is known to activate strong anti-apoptotic signaling pathways that promote oncogenesis. However, the role of Axl plays in osteosarcoma (OS) remains elusive. The present study...

journal_title：International journal of immunopathology and pharmacology

authors： Zhang Y,Tang YJ,Man Y,Pan F,Li ZH,Jia LS

更新日期：2013-01-01 00:00:00

abstract：:Nickel ingested with food can elicit either systemic cutaneous or gastrointestinal symptoms causing a systemic nickel allergy syndrome (SNAS) that can be treated with tolerance by oral ingestion of the metal. It has been suggested that interleukins 2 (IL-2) and 10 (IL-10) are involved in the mechanisms underlying oral...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardi L,Carni A,Loschiavo G,Gangemi S,Tigano V,Arena E,Mannucci C,Calapai G

更新日期：2013-01-01 00:00:00

abstract：:Overstrain tendonitis are common pathologies in the sport horses. Therapeutic approaches to tendon healing do not always result in a satisfactory anatomical and functional repair, and healed tendon is often characterized by functional impairment and high risk of reinjury. Recently, mesenchymal stem cells (MSCs) and pl...

journal_title：International journal of immunopathology and pharmacology

authors： Ricco S,Renzi S,Del Bue M,Conti V,Merli E,Ramoni R,Lucarelli E,Gnudi G,Ferrari M,Grolli S

更新日期：2013-01-01 00:00:00

abstract：:The expression of Ikaros family transcription factors and consequently their signalling pathway is limiting for hematopoietic and lymphocyte development in mice and human. Due to their importance, these transcription factors are highly homologous between species. As an initial approach to examining the possible involv...

journal_title：International journal of immunopathology and pharmacology

authors： Paradzik M,Novak S,Mokrovic G,Bordukalo Niksic T,Heckel D,Stipic J,Pavicic Baldani D,Cicin-Sain L,Antica M

更新日期：2012-10-01 00:00:00

abstract：:Cellular immune response has been demonstrated to play a role in the control of human cytomegalovirus (HCMV) replication in organ transplant recipients. Herein, HCMV-specific T-cell response and association to the onset of organ infection/disease were prospectively evaluated by EliSPOT assay in a population of 46 lung...

journal_title：International journal of immunopathology and pharmacology

authors： Costa C,Saldan A,Sinesi F,Sidoti F,Balloco C,Simeone S,Piceghello A,Mantovani S,Di Nauta A,Solidoro P,Cavallo R

更新日期：2012-10-01 00:00:00

abstract：:Four clinical cases regarding the correct diagnosis of early ocular Chlamydia trachomatis (Ct) inflammation, performed by two different modalities on the ocular ecosystem, are discussed. The present study was carried out in parallel using a cotton flock ocular swab and the scraping of upper lid conjunctiva. The ocular...

journal_title：International journal of immunopathology and pharmacology

authors： Gallenga PE,Del Boccio M,Lobefalo L,Rapinese M,Pennelli A,Martinotti S

更新日期：2012-10-01 00:00:00

abstract：:This study aimed to investigate the effects of a novel patented Mg-3Nd-0.2Zn-0.4Zr (weight %, JDBM) alloy on osteoblastic cell function, as these cells play an important role in bone repair and remodeling. The associated effects of the JDBM alloy on osteoblastic cell function involving cell adhesion, cell proliferatio...

journal_title：International journal of immunopathology and pharmacology

authors： Wang Y,Ouyang Y,Pang X,Mao L,Yuan G,Jiang Y,He Y

更新日期：2012-07-01 00:00:00

abstract：:Malacoplakia is a rare inflammatory condition characterized by the accumulation of benign macrophages associated with pathognomonic Michaelis-Gutmann bodies (MGBs). It is usually found in the genito-urinary tract, and has been associated with immunocompromised states. In this short report, we present 5 patients with p...

journal_title：International journal of immunopathology and pharmacology

authors： Mulè A,Petrone G,Santoro A,Sanguinetti M,Meacci E,Coli A,Margaritora S

更新日期：2012-07-01 00:00:00

abstract：:Vernal keratoconjunctivitis (VKC) is a severe chronic bilateral inflammation of the ocular surface characterized by seasonal exacerbations. Long-term prognosis is generally good; however, 6% develop sequelae responsible for permanent visual impairment. Corneal involvement is almost always present, consisting of puncta...

journal_title：International journal of immunopathology and pharmacology

authors： Caputo R,Pucci N,Mori F,De Libero C,Di Grande L,Bacci GM

更新日期：2012-07-01 00:00:00

abstract：:Hypertension has been suggested to exert pro-inflammatory actions through increased expression of several mediators, including chemokines. Chemokines are involved in inflammatory and autoimmune disorders, and in the formation of atherosclerotic lesions through promotion of inflammatory cell migration. The aim of this ...

journal_title：International journal of immunopathology and pharmacology

authors： Antonelli A,Fallahi P,Ferrari SM,Ghiadoni L,Virdis A,Mancusi C,Centanni M,Taddei S,Ferrannini E

更新日期：2012-04-01 00:00:00

abstract：:The objective of the study is to verify effects of nebulized 3% saline hypertonic solution (HS) in comparison to normal saline (NS) in addition to epinephrine in hospitalized children with bronchiolitis. Infants were randomly assigned either to receive every 6 hours nebulized NS (group I) or 3% HS (group II) in additi...

journal_title：International journal of immunopathology and pharmacology

authors： Miraglia Del Giudice M,Saitta F,Leonardi S,Capasso M,Niglio B,Chinellato I,Decimo F,Maiello N,Capristo C,Perrone L,Peroni D

更新日期：2012-04-01 00:00:00

abstract：:Type 1 diabetes (T1D) is a heterogeneous disorder characterized by destruction of pancreatic beta cells, culminating in loss of insulin secretion. Data from large epidemiologic studies worldwide indicate that during the last decades the incidence of T1D has increased significantly, reaching percentages of 2-5% annuall...

journal_title：International journal of immunopathology and pharmacology

authors： Piccini B,Toni S,Lenzi L,Guasti M,Barni F,De Martino M

更新日期：2012-04-01 00:00:00

abstract：:Antimuscarinic drugs are the first line pharmacotherapy for overactive bladder, but they are not always effective to achieve complete continence. Nevertheless in some patients urodynamic investigations reveal insufficient effects with continuing incontinence events even with dose optimization. The aim of this study is...

journal_title：International journal of immunopathology and pharmacology

authors： Nardulli R,Losavio E,Ranieri M,Fiore P,Megna G,Bellomo RG,Cristella G,Megna M

更新日期：2012-01-01 00:00:00

abstract：:Paracrine mediators released from endothelial progenitor cells (EPCs) have been implicated in neoangiogenesis following ischemia. Recently, we demonstrated that microvesicles (MVs) derived from EPCs are able to activate an angiogenic program in quiescent endothelial cells by a horizontal transfer of RNA. In this study...

journal_title：International journal of immunopathology and pharmacology

authors： Ranghino A,Cantaluppi V,Grange C,Vitillo L,Fop F,Biancone L,Deregibus MC,Tetta C,Segoloni GP,Camussi G

更新日期：2012-01-01 00:00:00

abstract：:Exhaled nitric oxide (FeNO) has been associated with bronchial eosinophilia and with airway hyperresponsiveness (AHR) in mild stable asthma. We previously demonstrated in a large project that allergen exposure is able to raise FeNO and to worsen AHR to bradykinin. We postulated that allergen-induced increase in FeN...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardolo FL,Di Stefano A,Silvestri M,Van Schadewijk AM,Malerba M,Hiemstra PS,Sterk PJ

更新日期：2012-01-01 00:00:00

abstract：:Icatibant, an antagonist of the bradykinin B2 receptor, was approved for the treatment of acute attacks of hereditary angioedema in the EU in 2008. This paper presents the case of a 65-year-old woman affected by frequent acute attacks of hereditary angioedema who benefitted from a change of therapy to icatibant, follo...

journal_title：International journal of immunopathology and pharmacology

authors： Firinu D,Barca MP,Serusi L,Lorrai MM,Peralta MM,Manconi PE,Del Giacco SR

更新日期：2012-01-01 00:00:00

abstract：:Cryopyrin-associated periodic syndromes are categorized as a spectrum of three autoinflammatory diseases, namely familial cold auto-inflammatory syndrome, Muckle-Wells syndrome and chronic infantile neurological cutaneous articular syndrome. All are caused by mutations in the NLRP3 gene coding for cryopyrin and result...

journal_title：International journal of immunopathology and pharmacology

authors： Cantarini L,Lucherini OM,Frediani B,Brizi MG,Bartolomei B,Cimaz R,Galeazzi M,Rigante D

更新日期：2011-10-01 00:00:00

abstract：:Both allergic disorders and obesity keep increasing in industrialized countries. Even though a strong association between obesity and allergy- related diseases has been reported in several studies, no published data show a scientific and firm link in-between the two conditions. In general, obesity and weight gain have...

journal_title：International journal of immunopathology and pharmacology

authors： Ciprandi G,Caimmi D,Raschetti R,Miraglia Del Giudice M,Salpietro C,Caimmi S,Castellazzi AM

更新日期：2011-10-01 00:00:00

abstract：:Arabinoxylan rice bran (MGN-3/Biobran) is a potent biological response modifier (BRM) that activates natural killer (NK) cells, T cells and monocytes. Currently, little is known regarding the effects of MGN-3 on dendritic cells (DCs), the cell type that bridges innate and adaptive immunity. Therefore, we examined the ...

journal_title：International journal of immunopathology and pharmacology

authors： Ghoneum M,Agrawal S

更新日期：2011-10-01 00:00:00

abstract：:Specific immunotherapy (SIT) is the only treatment able to not only act on the symptoms of allergy but also act on the causes. At present, SIT may be administered in two forms: subcutaneous (SCIT) and sublingual immunotherapy (SLIT). SCIT represents the standard modality of treatment while SLIT has recently been intro...

journal_title：International journal of immunopathology and pharmacology

authors： La Rosa M,Lionetti E,Leonardi S,Salpietro A,Bianchi L,Salpietro C,Miraglia Del Giudice M,Ciprandi G,Marseglia GL

更新日期：2011-10-01 00:00:00

abstract：:IgG4 have been hypothesized to act as blocking antibodies capable of preventing IgE-mediated effector cell triggering. This study aims to evaluate the changes in IgG4 in children during a period of natural antigen avoidance. Serum IgE and IgG4 were evaluated in a group of asthmatic children, aged between 7 and 17 year...

journal_title：International journal of immunopathology and pharmacology

authors： Piacentini GL,Guerresi S,Kantar A,Lubrano L,Olivieri F,Boner AL,Peroni DG

更新日期：2011-10-01 00:00:00

abstract：:The art of tattooing has increasing in recent decades. Allergic sensitivity to one of the pigments is the most frequent cause of dermatological reactions at the site of the tattoo. Gold is a new pigment used in tattooing, because of its bright yellow color and luster. Allergy to this metal is uncommon. To our knowledg...

journal_title：International journal of immunopathology and pharmacology

authors： Tammaro A,Tuchinda P,Persechino S,Gaspari A

更新日期：2011-10-01 00:00:00

abstract：:Blockade of the interactions between CD28/CTLA-4 and their ligands, CD80 (B7, B7.1)/CD86 (B70, B7.2), is an attractive means to induce antigen-specific peripheral tolerance in autoimmune disease and organ transplantation. In this study, we generated and characterized a monoclonal antibody (Clone 4E5) against human CD8...

journal_title：International journal of immunopathology and pharmacology

authors： Shi Q,Gao ZY,Xie F,Wang LF,Gu YP,Yang TJ,Huang L,Qian QH,Qiu YH

更新日期：2011-07-01 00:00:00

abstract：:Solid tumors such as head and neck squamous cell carcinoma (HNSCC) display an intense interaction between tumoral factors and the immune system. Functional modulation of tumor-infiltrating and peripheral blood immune cells plays an important role during tumor progression. In this pilot study we compared biological fun...

journal_title：International journal of immunopathology and pharmacology

authors： Trellakis S,Farjah H,Bruderek K,Dumitru CA,Hoffmann TK,Lang S,Brandau S

更新日期：2011-07-01 00:00:00

abstract：:Turner's syndrome (TS) is a genetic disorder caused by numeric and/or structural abnormalities of the X chromosome. In a previous study it was observed that acne is less frequent in TS than in the general population. Since the onset of acne in pre-pubertal or pubertal age is related to sebum production, this study eva...

journal_title：International journal of immunopathology and pharmacology

authors： Brazzelli V,Calcaterra V,Muzio F,Klersy C,Larizza D,Borroni G

更新日期：2011-07-01 00:00:00

abstract：:Surgical stress induces complex modifications in the hemodynamic, metabolic, neuro-hormonal and immune response of the individual. The magnitude of these alterations depends on preoperative events leading to surgery, the severity of surgical trauma, and also on post-operative/post-traumatic complications (multiple hit...

journal_title：International journal of immunopathology and pharmacology

authors： Cardinale F,Chinellato I,Caimmi S,Peroni DG,Franceschini F,Miraglia Del Giudice M,Bernardini R

更新日期：2011-07-01 00:00:00